In vitro analyses of suspected arrhythmogenic thin filament variants as a cause of sudden cardiac death in infants
Shafaattalab, S., Li, A.Y., Lin, E., Stevens, C.M., Dewar, L.J., Lynn, F.C., Sanatani, S., Laksman, Z., Morin, R.D., van Petegem, F., Hove-Madsen, L., Peter Tieleman, D., Davis, J.P., Tibbits, G.F. In vitro analyses of suspected arrhythmogenic thin filament variants as a cause of sudden [...]
Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease
Tam, A., Hughes, M., McNagny, K.M., Obeidat, M., Hackett, T.L., Leung, J.M., Shaipanich, T., Dorscheid, D.R., Singhera, G.K., Yang, C.W.T., Paré, P.D., Hogg, J.C., Nickle, D., Sin, D.D. Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease. View abstract.
Podocalyxin is required for maintaining blood–brain barrier function during acute inflammation
Cait, J., Hughes, M.R., Zeglinski, M.R., Chan, A.W., Osterhof, S., Wilder Scott, R., Hernaez, D.C., Cait, A., Wayne Vogl, A., Bernatchez, P., Michael Underhill, T., Granville, D.J., Murphy, T.H., Roskelley, C.D., McNagny, K.M. Podocalyxin is required for maintaining blood–brain barrier function during acute inflammation. [...]
Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation
Toselli, C.M., Wilkinson, B.M., Paterson, J., Kieffer, T.J. Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation. View Abstract.
Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues
Pereira, S., O’Dwyer, S.M., Webber, T.D., Baker, R.K., So, V., Ellis, C.E., Yoon, J.S., Mojibian, M., Glavas, M.M., Karunakaran, S., Clee, S.M., Covey, S.D., Kieffer, T.J. Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues. View abstract.
HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression
Patel, N., Wang, J., Shiozawa, K., Jones, K.B., Zhang, Y., Prokop, J.W., Davenport, G.G., Nihira, N.T., Hao, Z., Wong, D., Brandsmeier, L., Meadows, S.K., Sampaio, A.V., Werff, R.V., Endo, M., Capecchi, M.R., McNagny, K.M., Mak, T.W., Nielsen, T.O., Underhill, T.M., Myers, R.M., Kondo, T., [...]
In vivo characterization of doxycycline-mediated protection of aortic function and structure in a mouse model of Marfan syndrome-associated aortic aneurysm
Cui, J.Z., Lee, L., Sheng, X., Chu, F., Gibson, C.P., Aydinian, T., Walker, D.C., Sandor, G.G.S., Bernatchez, P., Tibbits, G.F., van Breemen, C., Esfandiarei, M. In vivo characterization of doxycycline-mediated protection of aortic function and structure in a mouse model of Marfan syndrome-associated aortic [...]
What triggers acute exacerbations of COPD? Why not ask the patient!
Milne, S., Sin, D.D. What triggers acute exacerbations of COPD? Why not ask the patient! View abstract.
Register now for Technological Platforms for Cell Therapy @ SFU
SFU, Centre for Cell Biology, Development, and Disease (C2D2) & BCRegMed are proud to sponsor Technological Platforms for Cell Therapy, at Simon Fraser University on March 6th, 2019. This event will bring together individuals in the BC RegMed community that are involved in cell [...]
Welcome Edwin Gershom | Manager, Partnerships and Innovation
BCREGMED would like to welcome Edwin Gershom who joined us in December in the role of Manager, Partnerships and Innovation. He will be located in the BRC building. His position is co-funded by CCRM and UBC and he will be responsible for supporting industry [...]
SBME Faculty Candidate Seminars – January 22, 2019
On Tuesday, January 22, 2019 between 8:30am and 12:05pm, candidates for the faculty of the School of Biomedical Engineering at UBC will be presenting their research seminars, followed by a discussion period in the Michael Smith Laboratories – Room 102 – 2185 East Mall. Faculty [...]
January News Blast | We’re Hiring + more great RegMed events
We're looking for a project coordinator who loves all things RegMed! Check out the latest posting in our January News Blast for more details. Some great events coming up, including The Medicine by Design Global Speaker Series with Peter Reddien, PhD, Massachusetts Institute of Technology, The Essential [...]
Save the date! Summer by Design 2019 workshop at UofT July 6-21, 2019
We are happy to announce that the Summer by Design 2010 workshop at the University of Toronto will run from July 6-21, 2019. The workshop is offered by Medicine by Design in partnership with CCRM and the Rotman School of Management. They will again [...]
Granzyme K expressed by classically activated macrophages contributes to inflammation and impaired remodeling
Turner CT, Zeglinski MR, Richardson KC, Zhao H, Shen Y, Papp A, Bird PI, Granville DJ. Granzyme K expressed by classically activated macrophages contributes to inflammation and impaired remodeling. J. Invest. Dermatol. doi: 10.1016/j.jid.2018.09.031. [Epub ahead of print] View Abstract
Talin autoinhibition regulates cell-ECM adhesion dynamics and wound healing in vivo
Haage A, Goodwin K, Whitewood A, Camp D, Bogutz A, Turner CT, Granville DJ, Lefebvre L, Plotnikov S, Goult BT, Tanentzapf G. Talin autoinhibition regulates cell-ECM adhesion dynamics and wound healing in vivo. 2018 Cell Rep. 27;25(9):2401-2416. DOI: 10.1016/j.celrep.2018.10.098 View Abstract
BCREGMED Winter Newsletter
Our final quarterly newsletter of 2019 is out! Check it out here The Winter newsletter features some great original content from our Trainee Steering Committee, exciting announcements and important dates for regenerative medicine events in 2019. Don't miss out, subscribe (form at the bottom [...]
USC Trainee Exchange
BCREGMED is proud to have sponsored our first student exchange with the University of Southern California. Christopher Luc (UVIC) recounts his experiences in the lab of Dr. Min Yu, Assistant Professor of Stem Cell Biology and Regenerative Medicine at the University of Southern California. This [...]
Project Coordinator
Temporary Full-Time (1.00 FTE) Start Date: January 15, 2019 End Date: January 14, 2020 Vancouver, BC Duties/Accountabilities: Participates in multiple projects and programs of multi-year projects; participates in initiatives in project management research, methodology, design, planning, implementation, integration, evaluation and ongoing monitoring. Arranges meetings [...]
UVIC Women in Science 2018 STEM Research Symposium Recap
UVic Women in Science (UVic WIS) is a student-led initiative focused on building a supportive and engaging network for women currently involved or interested in science, technology, engineering and math (STEM) fields. On November 29th, UVic WIS hosted its annual research event, the UVic WIS [...]
Biomedical Engineering Entrepreneurship Partnership (BEEP) Day
This past November 2nd 2018, the Centre for Biomedical Research (CBR) at the University of Victoria (UVic), hosted the 2nd Annual Biomedical Engineering Entrepreneurship Partnership Day, also known as BEEP Day in the Student Union Building at UVic. This event brings together startups and [...]
An interview with Dr. Connie Eaves
Earlier this year, at the meeting of the International Society for Stem Cell Research (ISSCR) in Australia, I had the chance to listen to Dr. Connie Eaves, Professor of Medical Genetics at the University of British Columbia (UBC) and Distinguished Scientist at the Terry [...]
Facial nerve regeneration using olfactory stem cells and hydrogels
Olfactory stem cells (OSCs) are neural stem cells found in the olfactory mucosa which have shown promising regenerative potential in spinal cord injury models by promoting axonal growth when engrafted into the injured area. Recently in a study published in Stem Cells Translational Medicine, [...]
Careers Column – An Interview with Keith Mewis (AbCellera Biologics)
Name: Keith Mewis Job title: Scientist, Robotics and Automation Company: AbCellera Biologics Describe a typical day in your position? What are some of your day-to-day activities? Our workflow is very high-throughput, so most of our molecular biology reactions are set up massively in parallel [...]
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