Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors
Krentz NAJ, Lee MYY, Xu EE, Sproul SLJ, Maslova A, Sasaki S & Lynn FC. Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors. Stem Cell Reports 11:1551-1564, 2018. DOI: 10.1016/j.stemcr.2018.11.008 View Abstract
Transdifferentiating Astrocytes Into Neurons Using ASCL1 Functionalized With a Novel Intracellular Protein Delivery Technology
Robinson M, Fraser I, McKee E, Scheck K, Chang L, Willerth SM. Transdifferentiating Astrocytes Into Neurons Using ASCL1 Functionalized With a Novel Intracellular Protein Delivery Technology. Front Bioeng Biotechnol. 2018 Nov 21;6:173.DOI: 10.3389/fbioe.2018.00173. eCollection 2018. View Abstract
Leptin contributes to the beneficial effects of insulin treatment in streptozotocin-diabetic male mice
Neumann UH, Kwon MM, Baker RK, Kieffer TJ. Am J Physiol Endocrinol Metab. 2018 Oct 9. doi: 10.1152/ajpendo.00159.2018. [Epub ahead of print] View Abstract
News Blast – November 2018
Our November news blast is out. Read about the 2018 Virtual Symposium, the 2018 trainee travel award winners and more. Find it here Previous blasts and newsletters
Dr. Fabio Rossi and Dr. Judy Illes: A consensus is building on how to move forward on stem cells (Repost)
This is a re-post of the Op-Ed published in the Vancouver Sun, written by Dr. Fabio Rossi & Dr. Judy Illes (Updated: October 10, 2018) We collectively propose the formation of a stem cell provider registry program, in which those who enroll certify that [...]
Congratulations to Chris Turner (Granville Lab), who has been awarded the 2018 AWTRS (Australasian Wound & Tissue Repair Society) Young Investigator Award
Post-Doctoral Fellow, Chris Turner (Granville Lab) was awarded the Australasian Wound & Tissue Repair Society (AWTRS) Young Investigator of the Year Award at the 2018 Cutaneous Biology Conference (Oct 29 - Nov 1, 2018) in Australia. Dr. Turner also received a 2018 BCREGMED Travel Award for [...]
Taking regulatory T-cell therapy one step further
Sicard A, Boardman DA, Levings MK. Curr Opin Organ Transplant. 2018 Oct;23(5):509-515. View Abstract
NHLBI 70th Anniversary Lecture Features Dr. George Q. Daley, the dean of Harvard Medical School
NHLBI - 70 Years of Disocvery 2018 marks the 70th Anniversary of the National Heart, Lung, and Blood Institute (NHLBI). NHLBI began as the National Heart Institute on June 16, 1948, when President Harry S. Truman signed the National Heart Act. In [...]
October is stem cell awareness month!
As part of stem cell awareness month the Stem Cell Network (SCN) has launched a new social media and outreach campaign using the hashtag #WeAreStemCells and the message: An investment in stem cell research is an investment in the future. This is our science. [...]
Dr. Fabio Rossi and Dr. Judy Illes: A consensus is building on how to move forward on stem cells
On Sept. 26, a small group representing both these communities from Canada and the U.S., as well as the government, gathered in Vancouver to identify common values in the area of stem-cell therapies, and agree on principles to move forward. Read the full article [...]
BCRegMed/Victoria Health Hackathon 2018
The first ever health and regenerative medicine themed Hackathon is being held in Victoria. Hackathons are focused events which bring together interdisciplinary teams to develop innovative solutions to front-line healthcare problems. We are recruiting hackers from all backgrounds and experiences, mentors, and judges. The kick-off [...]
Direct Reprogramming of Glioblastoma Cells into Neurons Using Small Molecules
Lee C, Robinson M, Willerth SM. ACS Chem Neurosci. 2018 Aug 22. [Epub ahead of print] View Abstract
The University of Victoria hosts a successful 34th annual meeting of the Canadian Society for Biomaterials
Dr. Stephanie M. Willerth, conference chair and the 2017-18 President of the Canadian Biomaterials Society (CBS), along with her organizing committee hosted the 34th Annual Meeting of CBS at the University of Victoria during May 16th through 19th. The meeting consisted of a 4-day [...]
Careers Column
Welcome to the BCRGEGMED Blog's Quarterly Career Column! Here we will feature career profiles with scientific professionals in British Columbia. In this issue, we interviewed Dr. Vincenzo Macri, Senior Scientist, Myogenic Group, STEMCELL Technologies. Describe a typical day in your position? What are your [...]
Tackling the world’s deadliest diseases one Ab at a time: An interview with AbCellera’s CEO, Dr. Carl Hansen
Dr. Carl Hansen, CEO of AbCellera, a Vancouver-based biotech on the hunt for novel antibodies. Can one company simultaneously work on solving the problems of Ebola, influenza, neurodegeneration, cancer, tuberculosis, and enterotoxicogenic E. coli? If you are AbCellera, a Vancouver-based biotech on [...]
Funding Opportunity:
FY18 Reconstructive Transplant Research Program (RTRP)
The office of Congressionally Directed Medical Research Programs (CDMRP) has recently released Fiscal Year 2018 (FY18) funding opportunities for the Department of Defense (DoD) Reconstructive Transplant Research Program (RTRP): Concept Award Investigator-Initiated Research Award Qualitative Research Award Detailed descriptions of the funding opportunity, evaluation [...]
Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction
Russo V, Klein T, Lim DJ, Solis N, Machado Y, Hiroyasu S, Nabai L, Shen Y, Zeglinski MR, Zhao H, Oram CP, Lennox PA, Van Laeken N, Carr NJ, Crawford RI, Franzke CW, Overall CM, Granville DJ. Sci Rep. 2018 Jun 26;8(1):9690. View Article
2018 BC Regenerative Medicine Symposium Follow Up
Our 2018 Symposium happened on May 9th at the Pharmaceutical Sciences Building at UBC! More than 220 attendees attended including scientists, trainees, and industry representatives from across Western Canada! Download the full Symposium booklet here! Or, simply download the Agenda here! Check [...]
Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing
Shen Y, Zeglinski MR, Turner CT, Raithatha SA, Wu Z, Russo V, Oram C, Hiroyasu S, Nabai L, Zhao H, Bozin T, Westendorf K, Kopko I, Huang R, Arns S, Tan J, Zeng H, Boey A, Liggins R, Jaquith J, Cameron DR, Papp A, [...]
NRC Postdoctoral Fellowship, 3D Bioprinting of Stem Cells City: Ottawa
The National Research Council is looking for a highly motivated PDF candidate to aid in the development of a novel, more physiologically relevant and predictive 3D human BBB preclinical model to aid in de-risking CNS drug development pipelines. Read more here
Bringing Human Induced Pluripotent Stem Cell Culture to the Masses
A major collaborative effort that brought together researchers from the Institutes for Integrated Cell-Material Sciences (iCeMS) and Frontier Medical Sciences in Kyoto University (Kyoto, Japan), the Institute for Stem Cell Biology and Regenerative Medicine (inStem) and the National Centre for Biological Sciences (NCBS) (Bangalore, [...]
A look into the exciting new world of 3D bioprinting: an interview with Aspect Biosystems’ CSO Dr. Sam Wadsworth
"3D bioprinting" sounds like something you would see in a science fiction movie, perhaps in "The Fifth Element" where the main character's body is fully printed in a giant bioreactor - bones, muscles and all - or else in "Starship Troopers" where, more modestly, [...]
A Conversation With Peter Zandstra,A PhD, FRSC(E)
A Conversation With Peter Zandstra,A PhD, FRSC(E) Peter Zandstra is a Professor of Biomedical Engineering, the Chief Technology Officer of ExCellThera, and the Chief Scientific Officer of the Center for Commercialization of Regenerative Medicine (CCRM). He is a renowned stem cell scientist and has [...]
“Patching” the Primate Spinal Cord With Human Neural Stem Cells
An interdisciplinary team made of neuroscientists, neurologists, and neurosurgeons, led by Dr. Mark Tuzynski at the University of California - San Diego (UCSD, San Diego, CA), reported this past February in Nature Medicine the successful grafting of human spinal cord-derived neural progenitor cells (NPCs) [...]
Using Human Kidney Organoids to Model Disease
Article reproducedA here from theA UBC Centre for Blood Research.A There is an urgent need for curative therapies to treat kidney failure. In 2015, over 21,000 patients in Canada received dialysis to treat kidney failure. Another 2,500 patients received a kidney transplant and 215 [...]
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