David is a Professor in the Department of Pathology and Laboratory Medicine at the University of British Columbia (UBC). He recently moved his laboratory to the International Collaboration On Repair Discoveries (iCORD) and was appointed as the Associate Director of the BC Professional Firefighters’ Burn and Wound Healing Group, Department of Surgery, UBC.
David’s research program over the past 20 years has been focused on mechanisms by which tissues are injured and identifying therapeutic targets that promote healing. More recently, he was inducted as a Scholar of the Royal Society of Canada. His research is focused on how aging, immobility and diabetes affect tissue injury, inflammation and repair. His research has identified a family of serine proteases, known as Granzymes (Granule-secreted enzymes) that are elevated and contribute to the pathogenesis in conditions associated with impaired healing and inflammation, including pressure/diabetic ulcers, nerve damage, vascular dysfunction and burn injury.