Localized Tacrolimus Delivery Repairs the Damaged Central Nervous System
Willerth SM. EBioMedicine. 2017 Dec;26:4-5. View Article
A repurposed drug could open door to more stem cell transplants
A medication used to treat joint and skin conditions might also help people whose only hope of surviving cancer is receiving stem cells from a donor, according to research by a University of British Columbia scientist. Transplants of blood stem cells, which can differentiate into all types of blood cells, can be a cure for life-threatening blood cancers like leukemia or lymphoma. But the treatment is often not pursued, because typical donations a often from umbilical cord blood a are unlikely to take root in a patienta s bone marrow and grow into a self-sustaining, blood-forming system. Researchers at UBC and [...]
Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell mediated TNFI signaling
Wang, W.,Fujii, H., et al., Zandstra, P.W. Science Translational Medicine.2017 Dec. 9:421 eaag3214 DOI: 10.1126/scitranslmed.aag3214 View Paper
FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors
Yoon, C., et al., Zandstra, P.W. Stem Cell Reports. 2018 Jan. 10:1-14. View Paper
Granzyme B in skin inflammation and disease
Turner CT, Lim D, Granville DJ. Matrix Biol. 2017 Dec 14. pii: S0945-053X(17)30335-9. Review. View Abstract
Recombinant Decorin Fusion Protein Attenuates Murine Abdominal Aortic Aneurysm Formation and Rupture
Shen, Y., et al., Granville, D. Nature Scientific Reports. 2017 Nov. 7:15857, DOI:10.1038/s41598-017-16194-8. View Paper
3-D Bioprinting of Neural Tissue for Applications in Cell Therapy and Drug Screening
Thomas M, Willerth SM. Front Bioeng Biotechnol. 2017 Nov 17;5:69. View Paper
Announcing the Bachelor of Applied Science in Biomedical Engineering at UBC!
The Bachelor of Applied Science in Biomedical Engineering program has received BC Ministry Approval! Read more about this exciting new program here!
Stem cells used in quest for new heart medications
By targeting your own specific stem cells, researchers aim to provide tailored treatments for individual atrial fibrillation patients. Dr. Zachary Laksman and his team have grown heart cells that can mimic abnormal heart rhythms. Hear more about this incredible research here.
Modeling the behavior of human induced pluripotent stem cells seeded on melt electrospun scaffolds
Hall ME, Mohtaram NK, Willerth SM, Edwards R. J Biol Eng. 2017 Oct 23;11:38. View Article