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Biomarker development in COPD: moving from p-values to products to impact patient care
Sin D, Hollander Z, DeMarco M, Sadatsafavi M, McManus BM, Ng, Raymond. CHESTA February 2017; 151(2):455-467. View paper
Myelin regulatory factor drives remyelination in multiple sclerosis
Greg J. Duncan, Jason R. Plemel,P eggy Assinck, Sohrab B. Manesh, Fraser G. W. Muir, Ryan Hirata, Matan Berson, Jie Liu, Michael Wegner, Ben Emery, G. R. Wayne Moore,A Wolfram Tetzlaff.A Acta Neuropathol. 2017,A doi: 10.1007/s00401-017-1741-7 Epub ahead of print. View Paper
Neuroprotection and secondary damage following spinal cord injury: concepts and methods
Hilton, BJ, Moulson, AJ, Tetzlaff, W. Neurosci.A Lets. 2017,652:3-10.A View Paper
Engineering cell fitness: lessons for regenerative medicine
Shakiba N, Zandstra PW.A Curr Opin Biotechnol. 2017 May 25;47:7-15. View paper
Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence
Rahman N, Brauer PM, Ho L, Usenko T, Tewary M, ZA?A iga-PflA?cker JC, Zandstra PW.A Nat Commun. 2017 May 25;8:15380. doi: 10.1038/ncomms15380 View Paper
The role of the innate immune response regulatory gene ABCF1 in mammalian embryogenesis and development
Wilcox SM, Arora H, Munro L, Xin J, Fenninger F, Johnson LA, Pfeifer CG, Choi KB, Hou J, Hoodless PA, Jefferies WA.A PLoS One.A 2017 May 19;12(5):e0175918 View Paper
Steric Hindrance Assay for Secreted Factors in Stem Cell Culture
Zhou W, Mahshid SS, Wang W, VallA e-BA lisle A, Zandstra PW, Sargent EH, Kelley SO.A ACS Sens. 2017 Apr 28;2(4):495-500. View Paper
Cell transplantation therapy for spinal cord injury
Assinck, P, Duncan, GJ, Hilton, BJ, Plemel, JR,A Tetzlaff, W.A Nat. Neurosci. 2017. (20) 637a 647A View Paper
Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors
Nicole A.J. Krentz, Dennis van Hoof, Zhongmei Li, Akie Watanabe, Mei Tang, Cuilan Nian, Michael S. German, Francis C. Lynn. Developmental Cell. 2017 Apr.A 41: 2, 129a 142. View paper.
Emerging biofabrication strategies for engineering of complex tissue constructs
Pedde, R.D., Mirani, B., Navaei, A., Styan, T., Wong, S., Mehrali, M., Thakur, A., Mohtaram, N.K., Bayati, A., Dolatshahi-Pirouz, A., Nikkhah, M.,A Willerth, S.M.A and Akbari, M.A Advanced Materials. 2017, April 3. View Paper
C-reactive protein and N-terminal prohormone brain natriuretic peptide as biomarkers in acute exacerbations of COPD leading to hospitalizations
Chen YR, Chen V, Hollander Z, Leipsic JA, Hague CJ, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD.
PLoS One. 2017 Mar 22;12(3):e0174063. View paper
Fibrin hydrogels induce mixed dorsal/ventral spinal neuron identities during differentiation of human induced pluripotent stem cells.
Edgar, J., Robinson, M., and Willerth, S.M. Acta Biomaterialia. 2017 Mar 15;51:237-245.A View abstract.A
Emerging biofabrication strategies for engineering of complex tissue constructs
Pedde, R.D., Mirani, B., Navaei, A., Styan, T., Wong, S., Mehrali, M., Thakur, A., Mohtaram, N.K., Bayati, A., Dolatshahi-Pirouz, A., Nikkhah, M., Willerth, S.M. and Akbari, M. Accepted at Advanced Biomaterials (Abstract Link Coming Soon)
Biomimetic strategies for replicating the neural stem cell niche.
Willerth, S.M.A Current Opinion in Chemical Engineering. View Abstract
Association of Serum MiR-142-3p and MiR-101-3p Levels with Acute Cellular Rejection after Heart Transplantation
Sukma Dewi I, Hollander Z, Lam KK, McManus JW, Tebbutt SJ, Ng RT, Keown PA, McMaster RW, McManus BM, GidlA f O, A hman J. PLoS One. 2017 Jan 26;12(1):e0170842. View paper
Enumerateblood – an R package to estimate the cellular composition of whole blood from Affymetrix Gene ST gene expression profiles
Shannon CP, Balshaw R, Chen V, Hollander Z, Toma M, McManus BM, FitzGerald JM, Sin DD, Ng RT, Tebbutt SJ.
BMC Genomics. 2017 Jan 6;18(1):43. View paper
A 17-gene stemness score for rapid determination of risk in acute leukemia
Ng, S., Mitchell, A., Kennedy, JA., Chen, WC., McLeod, J., Ibrahimova, N., Arruda, A., Popescu, A., Gupta, V., Schimmer, AD., Schuh, AC., Yee, KW., Bullinger, L., Metzeler, K., Herold, T., Cheok, M., Preudhomme, C., Dombret, H., Buske, C., LA wenberg, B., Valk, PJM., Zandstra, PW., Minden, MD., Dick, JE., Wang,JCY. A Nature. 2016 Dec 15;540(7633):433-437. View abstract
Functionalizing Ascl1 with novel intracellular protein delivery technology for promoting neuronal differentiation of human induced pluripotent stem cells.
Robinson, M., Chapani, P., Styan, T., Vaidyanathan, R., Willerth, S.M.A Stem Cell Reviews and Reports. 2016 12 (4) 476- 483. View Abstract
SABRE: a method for assessing the stability of gene modules in complex tissues and subject populations
Shannon CP, Chen V, Takhar M, Hollander Z, Balshaw R, McManus BM, Tebbutt SJ, Sin DD, Ng RT.
BMC Bioinformatics. 2016 Nov 14;17(1):460. View paper
Using functionalized transcription factors to engineer personalized neural tissue.
Willerth, S.M.A Neural Regeneration Research. 2016 Oct 11(10):1570-1571. View Abstract
This work was an invited commentary on our 2016 Stem Cell Reviews and Reports article.
Proneurogenic Ligands Defined by Modeling Developing Cortex Growth Factor Communication Networks
Yuzwa SA, Yang G, Borrett MJ, Clarke G, Cancino GI, Zahr SK, Zandstra PW, Kaplan DR, Miller FD. Neuron. 2016 Sep 7;91(5):988-1004.A View abstract
What are neural stem cells and why are they important?
Swayne, L-A., Sanchez-Arias, J., Agbay, A., and Willerth, S.M.A Frontiers for Young Minds. September 2016.
- Frontiers for Young Minds is an open access journal for youth aged 8-15. This article was the first one on stem cells in the Neuroscience section.
Distinguishing autocrine and paracrine signals in hematopoietic stem cell culture using a biofunctional microcavity platform
MA?ller E, Wang W, Qiao W, BornhA user M, Zandstra PW, Werner C, Pompe T. A Sci Rep. 2016 Aug 18;6:31951. View abstract
A Multi-Lineage Screen Reveals mTORC1 Inhibition enhances human pluripotent stem cell mesendoderm and blood progenitor production
Nazareth EJ, Rahman N, Yin T, Zandstra PW.A Stem Cell Reports. 2016 May 10;6(5):679-91. View abstract
Quality cell therapy manufacturing by design
Lipsitz YY, Timmins NE, Zandstra PW.A Biotechnol. 2016 Apr;3 4(4):393-400. View abstract